To encourage other researchers to use CORECT-R, our research programme will demonstrate what is possible in three key areas.
1. Supporting earlier diagnosis
Detecting bowel cancer early makes it far easier to treat. Therefore, we plan to:
- Link data from primary care, such as GP records, with cancer registry data to identify factors associated with a diagnosis of advanced bowel cancer.
- Analyse variations in colonoscopy use and outcome to inform practice.
- Compare the Bowel Cancer Screening Programmes of England, Scotland, Northern Ireland, and Wales to determine the best screening strategies.
2. Tackling inequalities
There are both national and international inequalities in bowel cancer. To determine variations, and to investigate why they arise, we plan to:
- Monitor the use of existing treatments as well as the uptake of new ones (such as robotic minimally-invasive surgery).
- Analyse the consistency of pathology reporting.
- Link clinical trial data, healthcare resource usage, patient reported outcome measures (PROMs) and other datasets to understand the long-term impact of cancer.
3. Optimising cancer research
We are collaborating with other researchers to make the best use of CORECT-R data. We plan to:
- Assist colleagues with linking genetic data with response to treatment and overall outcome.
- Work with clinical trial colleagues to follow up former trial participants within the context of the wider cancer population.
- Collaborate with the MRC Medical Bioinformatics Centre to bring together clinical data with non-healthcare datasets (such as consumer behaviour).